Condition Lookup
Sub-Category:
Dermatologic Disorders
Number of Conditions: 2
Cutaneous Manifestations of Hepatitis C
Specialty: Infectious Diseases
Category: Viral Hepatitis Complications
Sub-category: Dermatologic Disorders
Symptoms:
lichen planus; cryoglobulinemic vasculitis; porphyria cutanea tarda; necrotizing vasculitis; urticaria
Root Cause:
Immune-mediated responses or direct effects of chronic Hepatitis C virus (HCV) infection causing dermatologic manifestations.
How it's Diagnosed: videos
Hepatitis C serology (anti-HCV antibodies), HCV RNA PCR testing, skin biopsy for specific lesions.
Treatment:
Management of HCV with direct-acting antiviral agents (e.g., sofosbuvir, ledipasvir) combined with treatments specific to the dermatologic condition.
Medications:
Direct-acting antivirals (e.g., sofosbuvir —an HCV polymerase inhibitor; ribavirin —antiviral therapy). Dermatologic treatments include corticosteroids or immunosuppressants for inflammatory skin conditions.
Prevalence:
How common the health condition is within a specific population.
HCV affects approximately 1% of the global population; skin manifestations occur in 15–20% of those infected.
Risk Factors:
Factors or behaviors that increase the likelihood of developing the condition.
Chronic HCV infection, co-infection with other viruses, and poor immune response.
Prognosis:
The expected outcome or course of the condition over time.
Good with antiviral therapy; most dermatologic symptoms improve with successful HCV treatment.
Complications:
Additional problems or conditions that may arise as a result of the original condition.
Progressive liver disease, systemic vasculitis, and persistent skin conditions.
Dermatologic Manifestations of Rubella
Specialty: Infectious Diseases
Category: Viral Exanthems
Sub-category: Dermatologic Disorders
Symptoms:
pink, maculopapular rash; fever; lymphadenopathy; joint pain; red spots on the soft palate (forchheimer spots)
Root Cause:
Rubella virus infection causing immune-mediated skin and systemic reactions.
How it's Diagnosed: videos
Clinical evaluation of rash and symptoms, confirmed by rubella IgM antibodies or PCR.
Treatment:
Supportive care, as the disease is usually self-limiting. Vaccination is key for prevention.
Medications:
No specific antiviral therapy; symptomatic relief includes acetaminophen or NSAIDs for fever and pain.
Prevalence:
How common the health condition is within a specific population.
Reduced globally due to vaccination; still occurs in regions with low immunization rates.
Risk Factors:
Factors or behaviors that increase the likelihood of developing the condition.
Lack of vaccination, pregnancy (risk of congenital rubella syndrome), and close contact with infected individuals.
Prognosis:
The expected outcome or course of the condition over time.
Good for most individuals; self-limiting in immunocompetent hosts.
Complications:
Additional problems or conditions that may arise as a result of the original condition.
Arthralgia, encephalitis, congenital rubella syndrome in pregnant women.