Condition Lookup

Start typing to search for a specific condition, or select a specialty to see all of its conditions

Sub-Category:

Treponemal Diseases

Number of Conditions: 1

Treponematosis (Endemic Syphilis, Yaws, and Pinta)

Specialty: Infectious Diseases

Category: Bacterial Infections

Sub-category: Treponemal Diseases

Symptoms:
skin ulcers; bone and joint pain; skin discoloration (in pinta); progressive deformities in severe cases

Root Cause:
Caused by Treponema pallidum subspecies; spread through skin contact in non-sexual settings, primarily in tropical regions.

How it's Diagnosed: videos
Serologic tests (e.g., RPR, TPPA), dark-field microscopy of lesions, or PCR.

Treatment:
Penicillin G is the standard treatment; azithromycin or doxycycline may be alternatives.

Medications:
Benzathine penicillin G (beta-lactam antibiotic, long-acting); azithromycin (macrolide antibiotic, bacteriostatic ).

Prevalence: How common the health condition is within a specific population.
Common in certain tropical regions, particularly among children; yaws affects over 70,000 individuals globally.

Risk Factors: Factors or behaviors that increase the likelihood of developing the condition.
Living in tropical climates, lack of access to healthcare, poor hygiene.

Prognosis: The expected outcome or course of the condition over time.
Excellent if treated early; untreated cases can lead to severe deformities and disability.

Complications: Additional problems or conditions that may arise as a result of the original condition.
Bone and joint deformities, chronic skin ulceration, social stigma.