Condition Lookup
Sub-Category:
Targeted Infections
Number of Conditions: 1
Cytomegalovirus Organism-Specific Therapy
Specialty: Infectious Diseases
Category: Antiviral Treatment
Sub-category: Targeted Infections
Symptoms:
not applicable (focus is on treatment protocols).
Root Cause:
CMV causes significant morbidity in immunocompromised patients, necessitating targeted antiviral therapy.
How it's Diagnosed: videos
CMV DNA PCR, antigenemia assays, and culture methods to confirm active CMV infection.
Treatment:
Systemic antiviral drugs with specific regimens tailored to the severity and site of infection.
Medications:
Ganciclovir (DNA polymerase inhibitor), valganciclovir (oral prodrug of ganciclovir ), foscarnet (pyrophosphate analog), cidofovir (nucleotide analog).
Prevalence:
How common the health condition is within a specific population.
High among immunocompromised populations, such as transplant recipients and HIV-positive individuals.
Risk Factors:
Factors or behaviors that increase the likelihood of developing the condition.
Immunosuppression, congenital CMV, prolonged hospitalization.
Prognosis:
The expected outcome or course of the condition over time.
Effective therapy reduces morbidity and mortality in immunocompromised patients.
Complications:
Additional problems or conditions that may arise as a result of the original condition.
Drug resistance, nephrotoxicity, and recurrence of infection.