Condition Lookup
Sub-Category:
Filoviruses
Number of Conditions: 1
Ebola Virus Infection
Specialty: Infectious Diseases
Category: Viral Hemorrhagic Fevers
Sub-category: Filoviruses
Symptoms:
fever; severe headache; muscle pain; fatigue; diarrhea; vomiting; abdominal pain; unexplained bleeding or bruising
Root Cause:
Systemic infection caused by the Ebola virus, leading to vascular damage, coagulopathy, and immune system dysregulation.
How it's Diagnosed: videos
PCR testing for Ebola RNA, enzyme-linked immunosorbent assay (ELISA), antigen detection tests, and clinical signs in endemic areas.
Treatment:
Supportive care including fluids, electrolyte management, oxygen therapy, and blood products; antivirals like Inmazeb (monoclonal antibody combination) may be used.
Medications:
Inmazeb (monoclonal antibody therapy), mAb114 (monoclonal antibody), and experimental antiviral drugs under trial during outbreaks.
Prevalence:
How common the health condition is within a specific population.
Outbreaks primarily in sub-Saharan Africa; rare outside endemic areas.
Risk Factors:
Factors or behaviors that increase the likelihood of developing the condition.
Contact with infected individuals, handling contaminated body fluids, exposure to bats or other reservoir species, and poor infection control practices.
Prognosis:
The expected outcome or course of the condition over time.
Mortality rates range from 25% to 90%, depending on the strain and access to medical care. Survivors often experience long-term complications.
Complications:
Additional problems or conditions that may arise as a result of the original condition.
Multiorgan failure, shock, disseminated intravascular coagulation (DIC), and long-term sequelae such as joint pain and vision problems.