Background

Condition Lookup

Number of Conditions: 1

Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

Specialty: Infectious Diseases

Category: Neurological Autoimmune Disorders

Sub-category: Demyelinating Neuropathies

Symptoms:
progressive muscle weakness; sensory loss; areflexia; tingling sensations; difficulty walking or using limbs

Root Cause:
Autoimmune-mediated destruction of the myelin sheath surrounding peripheral nerves.

How it's Diagnosed: videos
Nerve conduction studies, electromyography (EMG), lumbar puncture with elevated CSF protein, and nerve biopsy if needed.

Treatment:
Immunomodulatory therapy including corticosteroids, intravenous immunoglobulin (IVIG), or plasmapheresis.

Medications:
Corticosteroids (e.g., prednisone ), IVIG (immune modulator), and immunosuppressants like azathioprine or rituximab in refractory cases.

Prevalence: How common the health condition is within a specific population.
Affects approximately 1–8 per 100,000 individuals worldwide.

Risk Factors: Factors or behaviors that increase the likelihood of developing the condition.
Age (more common in older adults), history of other autoimmune disorders, genetic predisposition.

Prognosis: The expected outcome or course of the condition over time.
Variable; many respond to treatment but may require long-term therapy to maintain remission. Relapses are common.

Complications: Additional problems or conditions that may arise as a result of the original condition.
Permanent neurological deficits, muscle atrophy, decreased mobility, and infections from long-term immunosuppression.