Background

Condition Lookup

Number of Conditions: 1

Drug Interactions with Antiretroviral Therapy (ART)

Specialty: Infectious Diseases

Category: Medication-Related Complications in HIV

Symptoms:
therapeutic failure of art; drug toxicity; unexpected adverse effects

Root Cause:
ART interacts with other medications via cytochrome P450 enzymes, transporters like P-glycoprotein, or through additive toxicities.

How it's Diagnosed: videos
Comprehensive medication review and clinical monitoring of drug efficacy and side effects.

Treatment:
Medication reconciliation, dose adjustments, or switching medications to reduce interactions.

Medications:
Interventions include using alternative ART regimens or prescribing agents to counteract interaction effects (e.g., boosters like cobicistat ).

Prevalence: How common the health condition is within a specific population.
Common in HIV patients due to the widespread use of polypharmacy.

Risk Factors: Factors or behaviors that increase the likelihood of developing the condition.
Polypharmacy, comorbid conditions, and inconsistent follow-up care.

Prognosis: The expected outcome or course of the condition over time.
Good with proper management; untreated interactions may lead to ART failure or toxicity.

Complications: Additional problems or conditions that may arise as a result of the original condition.
HIV progression, organ damage, or resistance development.