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Category:

Immune-mediated Disorders

Number of Conditions: 1

Poststreptococcal Glomerulonephritis

Symptoms:
swelling in the face and extremities; dark-colored urine; high blood pressure; fatigue; reduced urine output

Root Cause:
Immune response to Streptococcus infection leading to inflammation of glomeruli in the kidneys.

How it's Diagnosed: videos
Clinical history of recent strep infection, urine analysis (hematuria, proteinuria), and blood tests (low complement levels, elevated ASO titer).

Treatment:
Supportive care; addressing hypertension, fluid balance, and in rare cases, immunosuppressive therapy.

Medications:
Diuretics for fluid overload, antihypertensives (e.g., ACE inhibitors or ARBs) for blood pressure control. No direct antibiotic therapy unless active strep infection persists.

Prevalence: How common the health condition is within a specific population.
More common in children following strep throat or skin infections.

Risk Factors: Factors or behaviors that increase the likelihood of developing the condition.
Recent strep infections, especially in crowded or resource-limited settings.

Prognosis: The expected outcome or course of the condition over time.
Usually resolves with supportive care; chronic kidney damage is rare.

Complications: Additional problems or conditions that may arise as a result of the original condition.
Acute kidney injury, hypertensive encephalopathy, or nephrotic syndrome in severe cases.