Comprehensive Symptom Navigator™
Your health assistant, simplified.
Disclaimer: This is just an assistant. It should not be used for diagnosing patients without a doctor's discretion.
Symptoms:
Number of Conditions: 2
Hypereosinophilic Syndrome (HES)
Specialty: Hematology
Category: Immune System and Disorders
Symptoms:
fatigue; weight loss; skin rash; itching; cough; shortness of breath; cardiac symptoms like chest pain or heart failure
Root Cause:
Persistent overproduction of eosinophils leading to tissue damage in organs such as the heart, lungs, skin, and gastrointestinal tract.
How it's Diagnosed: videos
Persistent eosinophilia (greater than or equal to 1500/micro L for at least 6 months), clinical evaluation for organ damage, and exclusion of secondary causes like infections or malignancies.
Treatment:
Corticosteroids, immunosuppressive agents, and biologics targeting eosinophils (e.g., mepolizumab).
Medications:
Corticosteroids (e.g., prednisone for inflammation), tyrosine kinase inhibitors like imatinib (for specific molecular subtypes), and biologics like mepolizumab (anti-IL-5 monoclonal antibody).
Prevalence:
How common the health condition is within a specific population.
Rare; incidence is approximately 0.36–0.9 cases per 100,000 per year.
Risk Factors:
Factors or behaviors that increase the likelihood of developing the condition.
Genetic predisposition, male sex, and certain molecular mutations (e.g., PDGFRA rearrangements).
Prognosis:
The expected outcome or course of the condition over time.
Highly variable; manageable with treatment but may be life-threatening without intervention.
Complications:
Additional problems or conditions that may arise as a result of the original condition.
Cardiac complications (e.g., endomyocardial fibrosis), thromboembolism, and organ failure.
Leptospirosis
Specialty: Infectious Diseases
Category: Bacterial Infections
Symptoms:
high fever; muscle pain; headache; vomiting; jaundice; red eyes; skin rash; abdominal pain
Root Cause:
Caused by infection with Leptospira species, transmitted through water contaminated by animal urine, often affecting the liver, kidneys, and lungs.
How it's Diagnosed: videos
Serology (e.g., microscopic agglutination test), polymerase chain reaction (PCR), or culture from blood, urine, or cerebrospinal fluid.
Treatment:
Antibiotics to clear the infection, supportive care for organ involvement, and management of complications such as kidney failure.
Medications:
Doxycycline or penicillin (for mild cases); intravenous ceftriaxone or penicillin G for severe cases.
Prevalence:
How common the health condition is within a specific population.
Common in tropical and subtropical regions, particularly after heavy rainfall or flooding.
Risk Factors:
Factors or behaviors that increase the likelihood of developing the condition.
Exposure to contaminated water, working with animals, poor sanitation, recreational water activities.
Prognosis:
The expected outcome or course of the condition over time.
Good with early treatment; severe cases (Weil's disease) have a higher risk of mortality.
Complications:
Additional problems or conditions that may arise as a result of the original condition.
Kidney damage, meningitis, liver failure, respiratory distress, and hemorrhage.