Comprehensive Symptom Navigator™
Your health assistant, simplified.
Disclaimer: This is just an assistant. It should not be used for diagnosing patients without a doctor's discretion.
Symptoms:
Number of Conditions: 3
Acromegaly (leading to enlarged nasal and throat structures)
Specialty: Conditions with Overlap
Category: Certain systemic or generalized diseases have ENT manifestations
Sub-category: Endocrine and Metabolic Disorders
Symptoms:
enlarged nasal and throat structures (nasal passages, sinuses, and larynx); hoarseness; sleep apnea; snoring; thickened skin and features; joint pain and stiffness; excessive sweating; enlarged hands and feet
Root Cause:
Overproduction of growth hormone (GH) by the pituitary gland, usually caused by a benign pituitary tumor (adenoma). This results in abnormal growth of tissues, including those in the nasal and throat regions.
How it's Diagnosed: videos
Blood tests to measure levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1). MRI or CT scan of the pituitary gland to detect adenomas. Oral glucose tolerance test to assess GH suppression.
Treatment:
Surgery (transsphenoidal surgery) to remove the pituitary tumor. Radiotherapy to shrink the tumor if surgery is not fully successful. Medications to control growth hormone levels (somatostatin analogs or growth hormone receptor antagonists).
Medications:
Somatostatin analogs (e.g., octreotide , lanreotide ) are used to inhibit the secretion of growth hormone. Growth hormone receptor antagonists (e.g., pegvisomant ) block the effects of excess growth hormone. Dopamine agonists (e.g., bromocriptine ) may also be used to shrink tumors in some cases.
Prevalence:
How common the health condition is within a specific population.
Estimated to affect 3-4 people per million annually.
Risk Factors:
Factors or behaviors that increase the likelihood of developing the condition.
Genetic mutations (e.g., MEN1 syndrome), pituitary adenomas, family history.
Prognosis:
The expected outcome or course of the condition over time.
If treated early, the prognosis is good, and symptoms can be managed effectively. Untreated, acromegaly can lead to severe complications like cardiovascular disease and diabetes.
Complications:
Additional problems or conditions that may arise as a result of the original condition.
Cardiovascular problems (hypertension, heart failure). Diabetes or insulin resistance. Sleep apnea. Joint and bone problems (arthritis, carpal tunnel syndrome). Increased risk of colon cancer.
Pheochromocytoma and Paraganglioma
Specialty: Diabetes and Endocrinology
Category: Adrenal Disorders
Sub-category: Adrenal Hyperfunction
Symptoms:
episodic high blood pressure; headaches; palpitations; excessive sweating; anxiety or panic attacks; tremors; pale skin; weight loss
Root Cause:
Tumors in the adrenal medulla (pheochromocytoma) or extra-adrenal chromaffin tissue (paraganglioma) causing excessive secretion of catecholamines (epinephrine and norepinephrine).
How it's Diagnosed: videos
Diagnosed using plasma or urine metanephrines and imaging (CT/MRI).
Treatment:
Treated with surgical resection after preoperative alpha- and beta-blockade.
Medications:
Preoperative medications include phenoxybenzamine or doxazosin (alpha-blockers) and propranolol (beta-blocker) to manage symptoms.
Prevalence:
How common the health condition is within a specific population.
Rare, with an estimated prevalence of 0.1% in hypertensive patients.
Risk Factors:
Factors or behaviors that increase the likelihood of developing the condition.
Genetic mutations (e.g., MEN2, VHL, NF1), family history, and age (most common in adults aged 30–50).
Prognosis:
The expected outcome or course of the condition over time.
Good with early surgical treatment, but undiagnosed cases can be fatal due to hypertensive crises.
Complications:
Additional problems or conditions that may arise as a result of the original condition.
Cardiovascular complications (stroke, arrhythmias), multi-organ damage, and malignant transformation in rare cases.
Trichomycosis Axillaris
Specialty: Infectious Diseases
Category: Skin and Soft-Tissue Infections
Symptoms:
yellow, black, or red nodules on hair shafts in the axilla; foul odor; excessive sweating
Root Cause:
Bacterial infection of the hair shaft caused by Corynebacterium species.
How it's Diagnosed: videos
Clinical appearance, microscopic examination of hair shafts.
Treatment:
Good hygiene, shaving the affected area, and topical antibacterial agents.
Medications:
Topical clindamycin (lincosamide antibiotic) or benzoyl peroxide.
Prevalence:
How common the health condition is within a specific population.
Common in warm, humid climates.
Risk Factors:
Factors or behaviors that increase the likelihood of developing the condition.
Poor hygiene, hyperhidrosis, warm climates.
Prognosis:
The expected outcome or course of the condition over time.
Excellent with treatment and hygiene measures.
Complications:
Additional problems or conditions that may arise as a result of the original condition.
Persistent odor or recurrence if untreated.