Background

Condition Lookup

Sub-Category:

Stomach Lymphomas

Number of Conditions: 1

Lymphoma of the Stomach

Specialty: Gastrointestinal

Category: Stomach Disorders

Sub-category: Stomach Lymphomas

Symptoms:
abdominal pain; bloating; weight loss; nausea; vomiting; fatigue; fever; night sweats; loss of appetite

Root Cause:
Malignant proliferation of lymphoid tissue in the stomach, often linked to chronic H. pylori infection or immune suppression.

How it's Diagnosed: videos
Endoscopy with biopsy, histopathology, immunohistochemistry, imaging (CT, PET scan), and bone marrow biopsy for staging.

Treatment:
Eradication of H. pylori with antibiotics if associated, chemotherapy, radiation therapy, immunotherapy (e.g., rituximab), or a combination depending on the lymphoma type.

Medications:
Antibiotics (for H. pylori-associated cases, e.g., amoxicillin and clarithromycin ), rituximab (CD20 monoclonal antibody), and chemotherapy agents like cyclophosphamide , doxorubicin , vincristine , and prednisone (CHOP regimen).

Prevalence: How common the health condition is within a specific population.
Represents less than 5% of all stomach cancers, with a higher prevalence in individuals with chronic H. pylori infection.

Risk Factors: Factors or behaviors that increase the likelihood of developing the condition.
H. pylori infection, autoimmune disorders, immunosuppression, and family history of lymphoma.

Prognosis: The expected outcome or course of the condition over time.
Varies by type and stage; early-stage cases have a good prognosis, particularly with H. pylori eradication, while advanced cases depend on response to chemotherapy.

Complications: Additional problems or conditions that may arise as a result of the original condition.
Gastrointestinal bleeding, obstruction, perforation, and spread to lymph nodes or other organs.