Background

Condition Lookup

Sub-Category:

Macrocytic Anemia

Number of Conditions: 1

Folate Deficiency

Specialty: Hematology

Category: Nutritional Deficiencies and Disorders

Sub-category: Macrocytic Anemia

Symptoms:
fatigue; shortness of breath; pale skin; irritability; weakness; tongue swelling or soreness

Root Cause:
Insufficient folic acid intake or absorption disrupts DNA synthesis, particularly affecting red blood cell production.

How it's Diagnosed: videos
CBC with macrocytic anemia, serum folate levels, and homocysteine levels.

Treatment:
Dietary supplementation with folic acid and addressing underlying causes.

Medications:
Folic acid supplements (1 mg daily) and vitamin B12 supplements if a deficiency is concurrent.

Prevalence: How common the health condition is within a specific population.
Common in areas with poor nutrition; incidence is higher in pregnant women and alcoholics.

Risk Factors: Factors or behaviors that increase the likelihood of developing the condition.
Alcoholism, pregnancy, malabsorption syndromes, and certain medications (e.g., methotrexate).

Prognosis: The expected outcome or course of the condition over time.
Excellent with treatment; anemia resolves with supplementation.

Complications: Additional problems or conditions that may arise as a result of the original condition.
Severe anemia, neural tube defects in pregnancy, and cardiovascular risks from elevated homocysteine levels.