Background

Condition Lookup

Sub-Category:

Electrolyte Imbalance

Number of Conditions: 1

Phosphate Disorders

Specialty: Diabetes and Endocrinology

Category: Bone and Mineral Metabolism Disorders

Sub-category: Electrolyte Imbalance

Symptoms:
muscle weakness; bone pain; fatigue; confusion; seizures; irregular heartbeats

Root Cause:
Abnormal phosphate levels in the blood, either hypophosphatemia (low phosphate) or hyperphosphatemia (high phosphate), affecting cellular and skeletal functions.

How it's Diagnosed: videos
Blood tests to measure serum phosphate, calcium, and PTH levels; urine tests for phosphate excretion; assessment of vitamin D status and kidney function.

Treatment:
Treated by addressing the underlying cause, with hypophosphatemia managed using oral or intravenous phosphate supplementation, and hyperphosphatemia treated with phosphate binders, dietary restrictions, and managing associated conditions like kidney disease.

Medications:
Hypophosphatemia - Oral phosphate supplements (e.g., potassium phosphate or sodium phosphate) or intravenous phosphate for severe cases. Hyperphosphatemia - Managed with phosphate binders such as calcium acetate, calcium carbonate, sevelamer , lanthanum carbonate, or aluminum hydroxide, often alongside dietary phosphate restrictions and treatments for underlying conditions like chronic kidney disease.

Prevalence: How common the health condition is within a specific population.
Varies widely; hypophosphatemia is common in hospitalized patients and those with malnutrition, while hyperphosphatemia often occurs in individuals with chronic kidney disease (CKD).

Risk Factors: Factors or behaviors that increase the likelihood of developing the condition.
Kidney disease, malnutrition, alcohol dependency, vitamin D deficiency or excess, certain medications (e.g., diuretics or antacids).

Prognosis: The expected outcome or course of the condition over time.
Good with early recognition and management. Chronic untreated phosphate disorders can lead to long-term complications.

Complications: Additional problems or conditions that may arise as a result of the original condition.
For hypophosphatemia