Comprehensive Symptom Navigator™
Your health assistant, simplified.
Disclaimer: This is just an assistant. It should not be used for diagnosing patients without a doctor's discretion.
Symptoms:
Number of Conditions: 1
von Willebrand Disease
Specialty: Hematology
Category: Bleeding Disorders
Symptoms:
easy bruising; frequent nosebleeds; prolonged bleeding from cuts; heavy menstrual bleeding; excessive bleeding after surgery or dental procedures
Root Cause:
Deficiency or dysfunction of von Willebrand factor (vWF), leading to impaired platelet adhesion and secondary clotting defects.
How it's Diagnosed: videos
Coagulation studies (PT, aPTT), von Willebrand factor antigen and activity assays, and multimer analysis.
Treatment:
Desmopressin (DDAVP) for mild cases, vWF concentrates for severe cases, antifibrinolytics for bleeding prevention.
Medications:
Desmopressin (synthetic hormone to release stored vWF), vWF concentrates (replacement therapy), antifibrinolytics like tranexamic acid (to prevent breakdown of clots).
Prevalence:
How common the health condition is within a specific population.
Most common inherited bleeding disorder, affecting approximately 1% of the population.
Risk Factors:
Factors or behaviors that increase the likelihood of developing the condition.
Family history of von Willebrand disease.
Prognosis:
The expected outcome or course of the condition over time.
Generally good with appropriate management; most cases are mild.
Complications:
Additional problems or conditions that may arise as a result of the original condition.
Severe bleeding during surgery or trauma, menorrhagia-related anemia.